|
KMID : 0388419990090010107
|
|
Konkuk Journal of Medical Sciences
1999 Volume.9 No. 1 p.107 ~ p.112
|
|
|
The Value of Colposcopy in Screening Cervical Intraepithelial Neoplasia
|
|
Kim Soo-Nyung
|
|
|
Abstract
|
|
|
The Papanicolaou smear is the primary screening tool for cervical intraepithelial neoplasia (CIN) and invasive cervical cancer(ICC). False negative rates of Pap smear have been reported as high as 25-50%. Recent articles suggest that the use of colposcopy in addition to the Pap smear might improve the accuracy of CIN and ICC detection. However, colposcopic screening has not been practical because of its cost and the necessity of expertise in the evaluation of colposcopic findings. Because cervical rancor can be prevented by simple treatment of CIN, combined cytology and screening colposcopy is considered to be an important screening tool for CIN. The present study compared the usefulness of Pap smear with colposcopy in screening for CIN. Two hundred and forty-three gynecology patients were evaluated with cytology, colposcopy, and colposcopically directed biopsy. CIN and human papillomavirus infection were
diagnosed by biopsy. We excluded patients with a history of an abnormal Pap smear within the past 12 months, or a history of abnormal vaginal bleeding. Fifteen patients (6.2%) had CIN lesions diagnosed by colposcopically directed biopsies. In 13 patients condylomatous lesions were found, in 7 patients CIN Ⅰ, in 3 CIN Ⅱ, and in 5 patients CIN Ⅲ were diagnosed. Sensitivity and specificity rates of Pap smear were 66.7% and 97.8%, respectively. The corresponding figures for coloposcopy were 80.0% and 98.2％. The combination of both methods led to optimal sensitivity and specificity(100%,
respectively). Screening colposcopy is a valuable supplementary strategy for the detection of CIN, otherwise not detected with Pap smears.
|
|
|
KEYWORD
|
|
|
CIN, screening, colposcopy, pap smear
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|